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树突状细胞在炎症性肠病中的作用研究进展

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摘要 炎症性肠病(IBD)是以慢性、复发性肠道炎症为特征的疾病,包括克罗恩病和溃疡性结肠炎,它的发病原因及机制尚不明确[1].树突状细胞 (DCs)是迄今为止发现的抗原提呈能力最强的一类专职的抗原提呈细胞 (APC),它在启动免疫应答与诱导耐受过程中发挥关键作用[2-3].肠道DCs在识别细菌、诱导耐受及T细胞分化中起重要作用.本文就DCs在IBD中的作用研究进展进行了综述,旨在为临床预防与治疗IBD提供依据.
作者 肖瑶 金丹
出处 《延边大学医学学报》 CAS 2020年第2期148-151,共4页 Journal of Medical Science Yanbian University
基金 国家自然科学基金项目(No.81160367,81860288)。
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