南通市男男性行为人群新型毒品滥用和HIV感染状况调查

Analysis of Club Drug Abuse and HIV Infection Among Men Who Have Sex with Men in Nantong City

目的了解南通市男男性行为人群新型毒品滥用情况和HIV感染状况,为制定科学防控策略提供依据。方法采用滚雪球抽样等多种方式招募男男性行为(men who have sex with men,MSM)人群作为研究对象,进行问卷调查和血清学检测,调查内容包括人口学信息、性行为信息、新型毒品使用情况和HIV检测结果等。采用SPSS20.0进行χ^2检验和多因素Logistic回归分析,探讨MSM人群毒品使用以及HIV感染的影响因素。结果本次调查MSM 300人,平均年龄(32.18±8.87)岁,新型毒品使用率为64.00%(192/300),近半年98.50%(131/133)的人使用Rush Poppers(简称Rush)后发生过同性性行为。单因素分析显示同性恋性取向者新型毒品使用率较高(66.54%),不同年龄、婚姻状况、文化程度的人群新型毒品使用率之间差异无统计学意义。多因素Logistic回归分析显示年龄(OR=1.155,95%CI:1.011~1.318)、性取向(OR=15.907,95%CI:2.214~114.276)、同性性行为时安全套使用频率(OR=0.218,95%CI:0.054~0.882)是MSM人群HIV感染的影响因素。结论南通市MSM人群新型毒品的使用比例和HIV感染率较高,要加强对MSM人群新型毒品危害的警示性教育,制定有针对性的干预策略。

Objective To investigate the situation of club drug abuse and HIV infection among men who have sex with men(MSM)in Nantong,and to provide a scientific basis for the development of control strategies.Methods Three hundred MSM were recruited to conduct questionnaire and test HIV with various methods such as snowball technique.The questionnaire included socio-demographics,high-risk behaviors,club drug use and HIV infection.Chi-square test and multi-factor unconditional logistic regression model were used to analyze the influence factors of drug use and HIV infections.Results Among 300 MSM with an average age of 32.18±8.87 years,64.00%(192/300)were club drug user,98.50%(131/133)had homosexual behavior after using Rush in the past six months.Univariate analysis indicated that there were no statistically significant differences in the use of club drugs among MSM of different ages,marital status and educational level.The proportion of club drug users among MSM was higher(66.54%).The multi-factor unconditional logistic regression showed that age(OR=1.155,95%CI:1.011~1.318),sexual orientation(OR=15.907,95%CI:2.214~114.276)and frequency of condom use(OR=0.218,95%CI:0.054~0.882)were influence factors of HIV infections.Conclusion The proportion of club drug use and HIV infections among MSM in Nantong was relatively high.Targeted prevention strategies should focus on MSM abusing club drugs.