影响高脂血症性胰腺炎病情程度的因素分析

Analysis of the factors influencing the severity of hyperlipidemic pancreatitis

目的:分析高脂血症性胰腺炎(HLP)病情程度的影响因素。方法:纳入80例HLP病人为研究对象,其中31例(38.75%)病情进展为高血脂性急重症胰腺炎(HLSAP),纳为HLSAP组;病情稳定49例(61.25%)纳为HLP组。收集2组病人一般资料、血脂水平及其他实验室检查指标,分析病人住院期间病情进展情况,采用多因素logistic回归分析法分析HLP病人病情程度的独立影响因素。结果:多因素logistic回归分析显示,年龄、心率、呼吸频率、24 h尿量、APACHEⅡ评分、三酰甘油、白蛋白、血肌酐、血糖、动脉血氧分压是HLP病人病情程度的独立影响因素(P<0.05)。结论:年龄、心率、呼吸频率、24 h尿量、APACHEⅡ评分、三酰甘油、白蛋白、血肌酐、血糖、动脉血氧分压与HLP病情发展密切相关,临床应重视早期干预。

Objective:To analyze the influencing factors of the severity of hyperlipidemic pancreatitis(HLP).Methods:Eighty patients with HLP were divided into the hyperlipidemia severe acute pancreatitis group(HLSAP group,31 cases)and stable group(HLP group,49 cases).The general data,blood lipid level and other laboratory examination indexes were collected,the progress of patients′condition during hospitalization was analyzed,and the independent influencing factors of HLP patients′condition were analyzed using multiple logistic regression analysis.Results:The results of multiple logistic regression analysis showed that the age,heart rate,breathing rate,24 h urine volume,APACHEⅡscore,triglyceride,albumin,serum creatinine,blood glucose and arterial oxygen partial pressure were the independent factors influencing the severity of HLP patients(P<0.05).Conclusions:The age,heart rate,respiratory rate,24 h urine volume,APACHEⅡscore,triglyceride,albumin,creatinine,blood glucose and arterial oxygen partial pressure are closely related to the development of HLP.Early intervention should be emphasized in clinic.