广西钦州市慢性腰腿痛患者腰椎Modic改变的相关因素分析

Analysis of Related Factors of Lumbar Modic Changes in Patients with Chornic Lumbocrural Pain in Qinzhou City,Guangxi

目的:分析广西钦州市慢性腰腿痛患者腰椎Modic改变的相关因素。方法:选择2016年4月-2019年4月在区域性中心医院钦州市第一人民医院就诊的1520例慢性腰腿痛患者作为研究对象,根据MRI影像学诊断结果,将患者分成Modic改变组(n=257)和对照组(n=1263)。单因素分析两组患者的基线资料,对差异有统计学意义的单因素进行非条件logistic多因素回归分析,探究发生Modic改变的影响因素。结果:在1520例慢性腰腿痛患者中,257例患者出现Modic改变,发生率为16.91%。两组患者的年龄、性别、体质量指数、吸烟史、饮酒史、职业、冠心病、高血压、糖尿病、病程、Pfirrmann分级、椎间盘突出、Schmorl结节和腰椎滑脱比较,差异均有统计学意义(P<0.05)。logistic回归分析显示,年龄、体质量指数、Pfirrmann分级、椎间盘突出和职业是发生Modic改变的独立危险因素(P<0.05)。结论:年龄、体质量指数、Pfirrmann分级、椎间盘突出和职业是发生Modic改变的独立危险因素,临床宜针对上述因素制定切实可行并有针对性的干预措施,以降低慢性腰腿痛患者Modic改变发生率。

Objective:To analyze the related factors of lumbar Modic changes in patients with chornic lumbocrural pain in Qinzhou City,Guangxi.Method:A total of 1520 patients with chronic lumbocrural pain admitted to the First People’s Hospital of Qinzhou,a regional central hospital,from April 2016 to April 2019 were selected as study subjects.According to MRI imaging diagnosis,the patients were divided into Modic modified group(n=257)and control group(n=1263).Univariate analysis was performed on the baseline data of the two groups of patients,and non-conditional logistic multivariate regression analysis was performed on the univariate factors with statistically significant differences to explore the influencing factors for Modic changes.Result:Among 1520 patients with chronic lumbago and leg pain,Modic changes were found in 257 patients,with an incidence of 16.91%.Comparison of age,sex,body mass index,smoking history,drinking history,occupation,coronary heart disease,hypertension,diabetes mellitus,course of the disease,Pfirrmann grade,disc herniation,Schmorl nodule and lumbar spondylolismand between the two groups showed statistically significant differences(P<0.05).Logistic regression analysis showed that age,body mass index,Pfirrmann grade,disc herniation,and occupation were independent risk factors for Modic changes(P<0.05).Conclusion:Age,body mass index,Pfirrmann grade,disc herniation and occupation are independent risk factors for Modic change,and feasible and targeted intervention measures should be formulated for the above factors to reduce the incidence of Modic change in patients with chronic lumbocrural pain.