磁锚定辅助牵引技术在食管早癌内镜黏膜下剥离术中应用的初步研究

Primary study of endoscopic submucosal dissection with magnetic anchor technique for early esophageal cancer

目的目前,内镜黏膜下剥离术(ESD)已经成为消化道表浅癌的标准治疗方式,但对于食管病变,由于操作空间较为狭小,往往导致技术难度较大,手术耗时较长。本文报道了磁锚定牵引ESD治疗食管病变的初步结果。方法2020年4月至2020年6月,共计5例食管浅表癌患者于解放军总医院第一医学中心接受磁锚定牵引ESD,前瞻性收集患者相关信息。结果对于接受磁锚定牵引ESD的5例患者,整块切除率及完整切除率均为100%,R0切除率为80%,未见术中出血、术中穿孔、术后出血、术后穿孔等并发症发生。结论初步研究结果证实,磁锚定牵引ESD治疗食管病变是安全可行的,但仍需进一步大样本的研究印证上述观点,并同时评估其长期有效性。

Objective Endoscopic submucosal dissection(ESD)has become an established method for superficial neoplasm in digestive tract.However,there existed challenges in the procedures of ESD for superficial esophageal squamous cell neoplasm because of the narrow space.This study aimed to determine the feasibility and effectiveness of ESD with magnetic anchor technique(MAT)for superficial esophageal squamous cell neoplasm.Method Between April 2020 and June 2020,a total of 5 patients with superficial esophageal squamous cell neoplasm underwent ESD with MAT in our center,and related data was collected prospectively.Results For the five procedures of ESD with MAT,both complete dissection and en bloc resection rates were 100%,and R0 resection rate was 80%.No serous adverse events were encountered.Conclusion ESD with MAT was effective and feasible for superficial esophageal squamous cell neoplasm although further studies with larger sample size were needed.