煤焦油与银屑病

COAL TAR AND PSORIASIS

银屑病是一种慢性、炎症、免疫介导的多系统疾病,在世界范围内发病率约为1%~3%,中国患病率为0.47%。目前已有许多治疗方法,但均需长期维持治疗,对病人来说经济负担很重要,外用药物治疗是银屑病治疗的一线治疗方法。1925年,戈克曼首次描述了紫外线辐射联合煤焦油治疗银屑病的临床疗效,其结果是高清除率和长期缓解。虽然煤焦油的使用已经减少,但在许多地方仍然被认为是一线的处理方法。因为它容易获得,成本低,疗效相当好,且具有长期缓解作用。

Psoriasis is a chronic, inflammatory and immune-mediated multisystem disease with a worldwide incidence rate of about 1% to 3%. The prevalence rate in China is 0.47%. At present, there are many treatment methods, but long-term maintenance treatment is required, which is very important for patients’ economic burden. External drug therapy is the firstline treatment for psoriasis. In 1925, Goeckerman initial described for the clinical efficacy of ultraviolet radiation combined with coal tar in the treatment of psoriasis, with the result of high resolution and long-term remission. Although the use of coal tar has decreased, it is still considered as a first-line treatment method in many places. Because it is easy to obtain, low in cost, good in treatment effect, and has long-term relief effect.