右美托咪定联合布托啡诺在剖宫产术后镇痛中的应用效果分析

Analysis of the Effect of Dexmedetomidine Combined with Butorphanol in Analgesia after Cesarean Section

目的分析右美托咪定联合布托啡诺对接受足月剖宫产术的初产妇的镇痛效果。方法方便选择2016年1月—2019年1月该院收治的200例剖宫产初产妇,将其分为对照组(布托啡诺组)和试验组(右美托咪定联合布托啡诺组)。比较两组的镇痛、镇静效果和不良反应发生率。结果试验组术后1 h、术后2 h、术后6 h、术后12 h、术后24 h的VAS评分均显著低于同期对照组,差异有统计学意义(P<0.05),术后48 h内的不良反应发生率为11.00%,显著低于对照组27.00%,差异有统计学意义(χ^2=8.320,P<0.05);实验组术后1 h、术后2 h、术后6 h、术后12 h、术后24 h的Ramesay评分均显著高于同期对照组,差异有统计学意义(P<0.05)。结论右美托咪定联合布托啡诺可对剖宫产产妇发挥理想的镇痛和镇静效果,并减少不良反应发生。

Objective To analyse the analgesic effect of dexmedetomidine combined with butorphanol on primiparas undergoing term cesarean section.Methods A total of 200 primiparas received by cesarean section in the hospital from January 2016 to January 2019 were conveniently selected and divided into control group(butorphanol group)and test group(dexmedetomidine combined with butorphanol group).The analgesic and sedative effects and the incidence of adverse reactions between the two groups were compared.Results The VAS scores of the test group at 1 h,2 h,6 h,12 h,and 24 h after surgery were significantly lower than those of the control group at the same time,the difference was statistically significant(P<0.05).Adverse reactions within 48 h after surgery The incidence rate was 11.00%,which was significantly lower than that of the control group 27.00%,the difference was statistically significant(χ^2=8.320,P<0.05);the experimental group was 1 h after surgery,2 h after surgery,6 h after surgery,12 h after surgery,and 24 h after surgery.Ramesay scores were significantly higher than those of the control group,the difference was statistically significant(P<0.05).Conclusion Dexmedetomidine combined with butorphanol can exert an ideal analgesic and sedative effect on women undergoing cesarean section,and reduce the occurrence of adverse reactions.