全身炎症-免疫指数与维持性血液透析患者微炎症状态的关系

Relationship between Systemic Inflammation-immune Index and Microinflammatory State in Maintenance Hemodialysis Patients

目的:探讨维持性血液透析(MHD)患者全身炎症-免疫指数(SII)与微炎症状态的关系。结果:SII高组中性粒细胞计数、血小板计数、C-反应蛋白(CRP)及红细胞分布宽度(RDW)显著高于SII低组,而淋巴细胞计数、血红蛋白及白蛋白显著低于低SII组。MHD患者SII与CRP及RDW呈正相关,而与血红蛋白、白蛋白呈负相关。结论:SII可以反映MHD患者体内的微炎症状态,并且可以作为远期并发症干预治疗效果评估的参考指标。

Objective:To investigate the relationship between systemic inflammation-immune index(SII)and microinflammatory state in patients with maintenance hemodialysis(MHD).Results:The neutrophil count,platelet count,C-reactive protein(CRP)and red blood cell distribution width(RDW)were significantly higher in the high SII group than in the low SII group,while the lymphocyte count,hemoglobin and albumin were significantly lower in the low SII group.SII in MHD patients was positively correlated with CRP and RDW,but negatively correlated with hemoglobin and albumin.Conclusion:SII can reflect the state of microinflammation in MHD patients,and can be used as a reference index for the evaluation of long-term intervention effect of complications.