特发性颅内压增高的头痛特点分析

Analysis of headache characteristics of idiopathic intracranial hypertension

目的:研究特发性颅内压增高(idiopathic intracranial hypertension,IIH)的头痛特点。方法:连续收集2015年9月至2019年2月就诊于解放军总医院第一医学中心,明确诊断为特发性颅内压增高并伴有头痛症状的病人31例。收集病人一般人口学特点及临床资料并与国外同类研究比较。按照颅压升高程度分为两组(颅内压轻度升高组和颅内压重度升高组),比较两组间差异。结果:中、重度头痛25例(80.6%);双侧/全头痛21例(67.7%);头痛表型中偏头痛/可能的偏头痛18例(58.1%);颅内压轻度升高组与颅内压重度升高组相比两者在头痛程度、体重指数、性别分布无明显差异(P>0.05)。结论:IIH头痛以中-重度头痛为主,双侧/全头痛多见,偏头痛/可能的偏头痛是其主要头痛表型。颅内压升高的程度与头痛程度、体重指数、性别分布无明显相关性。

Objective:To explore the clinical characteristics of headache caused by idiopathic intracranial hypertension(IIH).Methods:From September 2015 to February 2019,31 patients definitely diagnosed with idiopathic intracranial hypertension complicated with headache were prospectively enrolled in the First Medical Center of Chinese PLA General Hospital.The general demographic characteristics and clinical data of the patients were collected and compared with similar studies abroad.The patients were divided into two groups according to the degree of elevation of intracranial pressure,and the differences between the two groups were compared.Results:Twenty-five cases were diagnosed with moderate or severe headache(80.6%),21 cases with bilateral or total headache(67.7%),18 cases with migraine or possible migraine in headache phenotype(58.1%).There was no significant difference in headache degree,body mass index,and sex distribution between the groups of mild elevated intracranial pressure and severe elevated intracranial pressure(P>0.05).Conclusion:The intensity of headache in IIH was mainly moderate to severe,and bilateral or total headache was most commonly observed.Besides,migraine or possible migraine was regarded as the main phenotype.Furthermore,the correlation between the degree of elevated intracranial pressure and the degree of headache,body mass index,and sex distribution were merely detected in this study.