慢性酒精中毒性脑病的临床诊治分析

Analysis of Clinical Diagnosis and Treatment of Chronic Alcoholic Encephalopathy

目的探究采用不同方法治疗慢性酒精中毒性脑病的疗效,并对诊断学特征进行汇总分析。方法方便选择该院2017年4月—2019年4月收治的40例慢性酒精中毒性脑病患者。按照治疗方法不同将所有研究对象分为参考组、实验组,每组20例。予以参考组患者维生素B1治疗,予以实验组患者维生素B1+醒脑静联合治疗。汇总所有患者的诊断学特征,比较两组患者的疗效、简易精神状态检查量表(MMSE)评分、生活质量量表(ADL)评分、不良反应发生情况等。结果所有患者均存在头部昏沉、心电异常情况。与参考组患者的70.0%相比较,实验组患者治疗总有效率95.0%更高,差异有统计学意义(χ^2=4.329,P=0.037)。与参考组患者的30.0%相比较,实验组患者不良反应发生率5.0%更低,差异有统计学意义(χ^2=4.329,P=0.037)。结论以维生素B1+醒脑静联合治疗慢性酒精中毒性脑病患者效果确切,可有效改善患者病情,降低患者不良反应发生率。

Objective To explore the efficacy of different methods in the treatment of chronic alcoholic encephalopathy, and to analyze the diagnostic features. Methods The 40 study subjects were selected from patients with chronic alcoholic encephalopathy who were admitted to the hospital from April 2017 to April 2019. According to different treatment methods,all research subjects were divided into two groups: reference group and experimental group, with 20 cases in each group.Patients in the reference group were treated with vitamin B1, and patients in the experimental group were treated with vitamin B1 and Xingnaojing. Summarize the diagnostic characteristics of all patients, compare the curative effect, Mini Mental State Examination Scale(MMSE) score, Quality of Life Scale(ADL) score, and adverse reactions between the two groups of patients. Results All patients had head dizziness and abnormal ECG. Compared with 70.0% of patients in the reference group, the total effective rate of treatment in the experimental group was 95.0% higher, the difference was statistically significant(χ^2=4.329, P=0.037). Compared with 30.0% of patients in the reference group, the adverse reaction rate of patients in the experimental group was 5.0% lower, the difference was statistically significant(χ^2=4.329, P=0.037).Conclusion The combination of vitamin B1 and Xingnaojing is effective in treating patients with chronic alcoholic encephalopathy, which can effectively improve the patient’s condition and reduce the incidence of adverse reactions in patients.