欣普贝生用于足月引产的临床疗效及不良反应情况分析

The Clinical Efficacy and Adverse Effects of Simpubesheng for Term Labor Induction

目的探讨欣普贝生用于足月引产的临床疗效及不良反应情况的影响。方法简单随机选取2017年5月—2019年5月入院期间收治的足月引产孕妇110例纳入研究,根据随机分组原则将其分为两组,每组55例,应用催产素引产的划分为参照组,给予欣普贝生引产的孕妇划分为实验组。对比两组孕妇经不同方式治疗后临床各项观察指标改善情况、引产成功率及不良反应发生率。结果实验组孕妇运用欣普贝生引产后临床各项观察指标改善情况均优于参照组应用催产素的孕妇,治疗后两组孕妇宫颈成熟评分、VAS疼痛评分、焦虑评分对比,差异有统计学意义(t=19.120、13.684、10.902,P<0.001);实验组自然分娩54例,成功分娩率为98.18%,参照组自然分娩47例,成功分娩率为85.45%,差异有统计学意义(χ^2=4.356,P=0.037),实验组孕妇引产成功率高于参照组;实验组不良反应发生2例,发生率为3.64%,参照组不良反应发生8例,发生率为14.55%,不良反应发生率低于参照组,差异有统计学意义(χ^2=3.960,P<0.05)。结论对足月引产的孕妇行欣普贝生引产其临床效果显著,有效地提升了引产成功率,减少了不良反应发生例数。

Objective To investigate the clinical efficacy and adverse effects of Simpubesheng for term induction of labor.Methods A total of 110 full-term pregnant women who were admitted to the hospital from May 2017 to May 2019 for induction of labor were random included in the study. They were divided into two groups according to the principle of randomization, with 55 cases in each group, and the reference group was divided into the reference group, the pregnant women who were given Simpubesheng to induce labor were divided into the experimental group. The improvement of clinical observation indicators, the success rate of labor induction and the incidence of adverse reactions were compared between the two groups of pregnant women after different treatments. Results The improvement of the clinical observation indexes of the pregnant women in the experimental group after induction of labor with Simpbex was better than that of the oxytocin pregnant women in the reference group. After treatment, the comparison of the cervical maturity score, VAS pain score and anxiety score of the two groups of pregnant women was statistically significantly difference(t=19.120, 13.684, 10.902, P<0.001);54 cases of natural delivery in the experimental group, the successful delivery rate was 98.18%, 47 cases in the reference group, the successful delivery rate was 85.45%,the difference was statistically significant(χ^2=4.356, P=0.037), the successful rate of pregnancy in the experimental group higher than the reference group;2 cases of adverse reactions occurred in the experimental group, with an incidence of 3.64%, 8 cases of adverse reactions occurred in the reference group, with an incidence of 14.55%, and the incidence of adverse reactions was lower than that of the reference group,the difference was statistically significant(χ^2=3.960, P<0.05). Conclusion The clinical effect of Simpbexon on pregnant women with full-term labor induction is significant, which effectively increases the success rate of labor induction and reduces the number of adverse reactions.