抽吸参数对电子烟气溶胶物理特性及人体呼吸道沉降的影响

Effects of puffing parameters on physical properties and deposition in human respiratory tract of e-cigarette aerosols

为研究抽吸参数对电子烟气溶胶物理特性及其在人体呼吸道沉降的影响,采用吸烟循环模拟机-快速粒径谱仪测试电子烟气溶胶的物理特性,并利用多路径粒子剂量测定模型对气溶胶进行沉降模拟,考察了抽吸持续时间(2、3、4 s)、抽吸容量(35、55、75 mL)和抽吸间隔(30、60 s)对电子烟气溶胶物理特性及其在人体呼吸道沉降的影响。结果表明:①随着抽吸持续时间的延长,电子烟气溶胶的粒数浓度及粒径明显增加,其在人体呼吸道的沉降量也呈增加趋势;②随着抽吸容量的增加,电子烟气溶胶粒数浓度增加而粒径变小,沉降系数及沉降粒数浓度增加而沉降质量浓度先增加后降低;③抽吸间隔对电子烟气溶胶物理特性及气溶胶在人体呼吸道沉降的影响较小。

To investigate the influences of puffing parameters on the physical properties and deposition in human respiratory tract of electronic cigarette(e-cigarette)aerosols,e-cigarettes were smoked by simulating human smoking under six puffing regimes at different puff durations(2,3,4 s),puff volumes(35,55,75 mL)and puff intervals(30,60 s).The results showed that:1)With the increase of puff duration,the particle number concentration and particle size of the aerosols raised significantly,which further increased the amount of aerosol deposition in human respiratory tract.2)At a higher puff volume,the particle number concentration of the aerosols increased,while the particle size decreased;and the deposition fraction and deposition particle number concentration increased,while deposition particle mass concentration slightly decreased.3)Puff interval slightly influenced the physical properties and deposition in human respiratory tract of e-cigarette aerosols.