48例灰质异位症的临床及影像学特点分析

Clinical and imaging charaCTeristics of 48 cases of gray matter heterotopia

目的:探讨灰质异位症(GMH)的临床及影像学特点,提高临床医生对该病的认识。方法:对2016年1月—2020年7月就诊的48例GMH患者进行回顾性研究。总结其临床及影像学特点。结果:我们根据位置和形态不同将GMH分为5型:①室管膜下型(27例);②局灶性皮下型(10例);③弥漫型(3例);④脑裂畸形型(3例);⑤混合型(5例)。GMH还常可并发其它的一些颅脑畸形。结论:结合癫痫发作的病史及影像学表现,MRI对不同类型的GMH诊断有重要价值。

Objective To investigate the clinical and imaging features of gray matter heterotopia(GMH)and improve the clinicians understanding of the disease.Methods A retrospeCTive study was performed on 48 patients with GMH diagnosed from January 2016 to July 2020.Their clinical and imaging features are also summarized.Results GMH were classified into five types according to their locations and shapes:Subependymal type(14 cases),Focal type(4 cases),Diffuse type(1 case),Schizencephaly type(2 cases),Multiple type(2 cases).GMH also concluded other craniocerebral malformation.Conclusion GMH can be diagnosed according to the history of seizures as well as MRI performances.