摘要
目的:分析阿卡波糖引起不良反应(adverse drug reactions,ADR)的原因和规律,为临床合理使用提供参考。方法:检索中国知网数据库和万方数据库关于阿卡波糖ADR的个案报道并进行统计分析。结果:阿卡波糖所致ADR个案报道共计17例;其年龄分布以大于45岁年龄段最多(15例,88.24%);ADR多发生在用药后1周内(70.59%);阿卡波糖所致ADR累及系统前两位分别为皮肤及其附件(35.71%)和消化系统(35.71%)。结论:应重视阿卡波糖所致ADR,加强用药监测,提高患者用药风险意识,降低ADR的严重程度。
Objective:To analyze the cause and pattern of adverse drug reactions(ADR)caused by acarbose,and to provide reference for clinical rational use.Methods:The case reports about ADR of acarbose were retrieved from CNKI database and Wanfang database for statistics and analysis.Results:17 ADR cases caused by acarbose were analyzed.Most cases distributed in the age group over 45 years old(15 cases,88.24%).ADR usually occurs within one week after medication(70.59%).The top two involved systems of acarbose ADR were skin and its accessories damage(35.71%)and digestive system(35.71%).Conclusion:We should pay more attention to ADR of acarbose,strengthen the monitoring of drug use,improve patients awareness of drug risk and reduce the severity of ADR.
作者
张文鑫
王奎鹏
曹英杰
ZHANG Wen-xin;WANG Kui-peng;CAO Ying-jie(The First Affiliated Hospital of the Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China)
出处
《中国合理用药探索》
CAS
2020年第10期7-10,共4页
Chinese Journal of Rational Drug Use
基金
国家自然科学基金青年科学基金资助项目(81603431)。
关键词
阿卡波糖
不良反应
文献分析
个案报道
用药安全
acarbose
adverse drug reaction
literature analysis
case report
safe drug use
