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血清sTREM-1、sCD163水平对老年烧伤患者并发脓毒症的诊断价值 被引量:10

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摘要 目的探究血清可溶性髓样细胞表达的激发受体(sTREM)-1、可溶性血红蛋白清道夫受体(sCD163)水平对老年烧伤患者并发脓毒症的诊断价值。方法选择131例老年烧伤患者作为研究对象,根据患者是否并发脓毒症将患者分为非脓毒症组和脓毒症组。采用血细胞自动分析仪分析患者的血常规指标,采用酶联免疫吸附试验检测血清sTREM-1和sCD163。Logistic回归分析老年烧伤患者并发脓毒症的危险因素,采用受试者工作特征(ROC)曲线分析指标的诊断价值。结果与非脓毒症组相比,脓毒症组的总烧伤面积、sTREM-1和sCD163水平明显升高(P<0.05)。Logistic回归分析结果显示总烧伤面积、血清sTREM-1水平和sCD163水平是并发脓毒症的主要危险因素(P<0.05)。血清sTREM-1、sCD163水平对老年烧伤患者并发脓毒症的ROC曲线显示,曲线下面积(AUC)分别为0.796、0.826,灵敏度和特异度分别为83.4%、78.4%,80.3%、83.8%,联合诊断的灵敏度和特异度分别为88.2%、86.2%。结论老年烧伤并发脓毒症患者血清sTREM-1和sCD163水平明显升高,并且与脓毒症的发生密切关联。血清sTREM-1和sCD163水平对老年烧伤并发脓毒症具有较高的诊断敏感性和特异性,在老年烧伤并发脓毒症的诊断中具有一定的临床意义。
出处 《中国老年学杂志》 CAS 北大核心 2020年第21期4570-4574,共5页 Chinese Journal of Gerontology
基金 国家自然科学基金项目(81660320)。
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