儿童ERCP术后胰腺炎危险因素的研究进展

Progress on risk factors of post-endoscopic retrograde cholangiopancreatography pancreatitis in children

内镜下逆行胰胆管造影术(endoscopic retrograde cholangiopancreatography,ERCP)近年来逐渐成为儿童先天性胆胰疾病以及急性复发性胰腺炎(acute recurrent pancreatitis,ARP)的主要诊治手段,其中ERCP术后胰腺炎(post-ERCP pancreatitis,PEP)是ERCP术后最常见的并发症,少数严重者可发展为重症急性胰腺炎危及患儿生命,因此识别儿童PEP危险因素具有重要临床意义。已报道的PEP危险因素众多,包括内镜括约肌切开术(endoscopic sphincterotomy,EST)、胰管造影剂快速多次注射、预防性胰管支架以及操作者经验缺乏等。该文将对PEP危险因素的研究进展作一综述。

In recent years,endoscopic retrograde cholangiopancreatography(ERCP)has gradually become the main diagnosis and treatment for congenital biliopancreatic diseases as well as acute recurrent pancreatitis(ARP)in children.Post-ERCP pancreatitis(PEP)is the most common complication,and a few can develop severe acute pancreatitis endangering the children′s life,so it is of great clinical significance to identify the risk factors for PEP in children.Various factors associated with PEP were identified in pediatric patients,such as endoscopic sphincterotomy(EST),rapid multiple injections of pancreatic duct contrastagents,prophylactic pancreatic duct stents,and lack of operator experience.This article reviews the progress on risk factors of PEP.