补气通络方治疗气虚痰瘀型脑梗死的疗效观察及其对同型半胱氨酸的影响

Clinical Observation on Cerebral Infarction of Qi Deficiency and Phlegm and Blood Stasis Syndrome Treated with Buqi Tongluo Prescription(补气通络方)and Effect on Homocysteine

目的:观察补气通络方治疗气虚痰瘀型脑梗死的临床疗效及其对同型半胱氨酸的影响。方法:选择气虚痰瘀型脑梗死恢复期患者80例,随机分为对照组和观察组各40例,对照组给予西医常规康复治疗,观察组在对照组治疗基础上加用补气通络方,治疗1月后评定疗效;治疗前后进行两组患者神经功能缺损(NIHSS)评分、中医证候评分及同型半胱氨酸检测。结果:观察组总有效率为90%,对照组总有效率为73%,观察组疗效显著优于对照组,差异具有统计学意义(P<0.05)。观察组治疗后NIHSS评分、中医证候评分及血同型半胱氨酸水平均低于治疗前并低于同期对照组(P<0.05)。结论:补气通络方能提高气虚痰瘀型脑梗死的临床疗效,并降低同型半胱氨酸水平。

Objective:To observe the curative effect of cerebral infarction of Qi Deficiency and Phlegm and Blood Stasis Syndrome patients treated with Buqi Tongluo Prescription(BTP)and effect on homocysteine.Methods:80 patients with cerebral infarction of Qi Deficiency and Phlegm and Blood Stasis Syndrome were selected and randomly divided into control group and observation group with 40 cases for each.The control group were treated with routine Western medicine therapy and the observation group were treated with BTP on the basis of the control group’s therapy,they were treated for 1 month,then evaluated the curative effect,the neural function defect score(NIHSS),the syndrome score of TCM syndroem and serum homocysteine level were determined before and after treatment.Results:The total effective rate was 90%in the observation group and 73%in the control group,and the curative effect of the observation group was significantly better than that of the control group(P<0.05).After treatment,the NIHSS score,the TCM syndrome score and the homocysteine level in the observation group were all lower than those before treatment and those in the control group at the same time.Conclusion:BTP could improve the curative effect of cerebral infarction with Qi Deficiency and Phlegm and Blood Stasis Syndrome,and reduce the homocysteine level.