自拟活血化瘀汤加减联合西药治疗急性脑出血(瘀水阻窍证)的临床效果

Clinical effect of modified self-designed Huoxue Huayu decoction combined with western medicine in the treatment of acute cerebral hemorrhage(stasis and obstruction syndrome)

目的探讨自拟活血化瘀汤加减联合西药治疗急性脑出血(瘀水阻窍证)的临床效果。方法纳入2015年1月1日至2019年12月31日我院收治的500例急性脑出血(瘀水阻窍证)患者为研究对象,根据治疗方法的不同将其分为常规组和联合用药组,每组250例。常规组采用注射用七叶皂苷钠治疗,联合用药组采用注射用七叶皂苷钠联合自拟活血化瘀汤加减方治疗。比较两组的治疗效果。结果治疗7 d后,两组NIHSS评分均低于治疗前,且联合用药组明显低于常规组(P<0.05);治疗14 d后,两组NIHSS评分均低于治疗7 d后,且联合用药组低于常规组(P<0.05)。治疗14 d后,两组APACHEⅡ评分均低于治疗前,且联合用药组低于常规组(P<0.05)。结论自拟活血化瘀汤加减联合西药治疗急性脑出血(瘀水阻窍证)患者,可明显改善NIHSS评分和APACHEⅡ评分,促进神经功能恢复,提高临床治疗效果。

Objective To investigate the clinical effect of modified self-designed Huoxue Huayu decoction combined with western medicine in the treatment of acute cerebral hemorrhage(stasis and obstruction syndrome).Methods A total of 500 patients with acute cerebral hemorrhage(stasis and obstruction syndrome)admitted in our hospital from January 1,2015 to December 31,2019 were selected as the research objects.According to different treatment methods,the patients were divided into conventional group and combined medication group,with 250 cases in each group.The conventional group was treated with sodium aescinate for injection,while the combined medication group was treated with sodium aescinate for injection combined with modified self-designed Huoxue Huayu decoction.The therapeutic effects of the two groups were compared.Results After 7 d of treatment,the NIHSS scores of the two groups were lower than those before treatment,and that in the combined medication group was significantly lower than the conventional group(P<0.05);after 14 d of treatment,the NIHSS scores of the two groups were lower than those after 7 d of treatment,and that in the combined medication group was lower than the conventional group(P<0.05).After 14 d of treatment,ApacheⅡscores of the two groups were lower than those before treatment,and that of the combined medication group was lower than the conventional group(P<0.05).Conclusion The modified self-designed Huoxue Huayu decoction combined with western medicine in the treatment of patients with acute cerebral hemorrhage(stasis and obstruction syndrome)can significantly ameliorate NIHSS and ApacheⅡscores,promote the recovery of neurological function and improve the clinical therapeutic effect.