健康体检人群胸部低剂量螺旋CT检出肺部结节及肺癌情况研究

Analysis of the result of pulmonary nodules and lung cancer detected by low-dose spiral CT in healthy examination people

目的了解健康体检人群行胸部低剂量螺旋CT检出肺结节、及检出肺结节后诊断为肺癌的情况。方法对2018年1月至2019年7月在川北医学院附属医院行胸部螺旋CT的10642名健康体检人群进行回顾性分析,筛查出检出肺部结节患者,并按照筛查结果,分别按年龄段、性别、结节大小分组,比较肺结节及肺癌检出率。结果共检出肺部结节2857例,检出率达26.8%,男女肺结节检出率分别为27.4%及26.8%,差异无统计学意义。随年龄增长,肺结节检出率呈上升趋势,但在60岁之后结节检出率趋于稳定。肺癌总检出率1.915‰,筛查出的肺癌中腺癌占76%。结论胸部低剂量螺旋CT有助于健康体检人群早期肺癌检出,对高危肺部结节积极随访、处理有利于发现早期肺腺癌。低剂量螺旋CT应在40岁后健康人群中积极开展,男女性别同等重要。

Objective To investigate the pulmonary nodules detected by low-dose spiral CT and the pulmonary nodules diagnosed as lung cancer in healthy examination people.Methods A retrospective analysis was conducted on 10642 healthy people who received chest low-dose spiral CT examination in the affiliated hospital of North Sichuan medical college from January 2018 to July 2019.According to the results of screening,the detection rates of pulmonary nodules and lung cancer were compared among the groups of individuals of different gender,age,nodule size and pathlogical type of lung cancer respectively.Results 2857 pulmonary nodules were detected,and the total detection rate was 26.8%.The detection rates of pulmonary nodules in male and female showed no statistically significant difference(27.4% VS 26.8%).The detection rate of pulmonary nodules increased with age,but the trend became stable after 60 years old.The overall detection rate of lung cancer was 1.195%,and adenocarcinoma accounting for 76%.Conclusion Lung cancer screening with low-dose spiral CT can improve the early detection rate of lung cancer,and active follow-up of high-risk pulmonary nodules is helpful for early detection of lung Adenocarcinoma,which should be actively carried out in healthy people after the age of 40,and male and female are equally important.