甘肃部分地区莱姆病血清流行病学及相关因素调查研究

Investigation of seroepidemiology of Lyme disease and related factors in some regions of Gansu province

目的调查了解甘肃省部分地区人群感染莱姆病螺旋体情况及相关因素。方法收集调查点内人群血液标本,采用间接免疫荧光法进行血清抗体检测;所有被调查者均完成相关调查表,以了解其对疾病的知晓情况及是否采取保护措施。结果共收集血液标本426份,间接免疫荧光检测阳性共33例,阳性率为7.75%,不同职业人群阳性率不同,以林业工人的阳性率为高。调查表结果显示:90%的参与者有蜱暴露史,林业工人被蜱叮咬人数是其他人的2.5倍(χ^2=40.25,P<0.001)。采取不同保护措施的人群血清阳性率不同。结论调查点内存在莱姆病,当地人群可能会受该病的威胁。

Objective To explore the prevalence of Lyme disease spirochete and related factors in population in some regions of Gansu Province.Methods Blood samples were collected from the population within the investigation site,and indirect immunofluorescence was used for the detection of the serum antibodies.All participants completed relevant questionnaires to have the investigators know their awareness of the disease and whether they have taken protective measures.Results A total of 426 blood samples were collected,of which 33 samples showed positive results in the detection with indirect immunofluorescence,the positive rate was 7.75%.Population with different occupations had different positive rates,among which,the forestry workers ranked the first.According to the questionnaire results,90%of participants had a history of tick exposure,and the number of forestry workers bitten by ticks were 2.5 times higher than others(χ~2=40.25,P<0.001).The seropositive rates were different among population taking different protective measures.Conclusion Lyme disease is present within the investigation site,and may pose a risk to the local population.