肝内胆管结石术后复发的研究进展

Research progress of postoperative recurrence of intrahepatic cholelithiasis

肝内胆管结石(IBDS)是临床肝胆外科常见疾病,是我国良性胆道疾病重要的致死原因。其治疗方式以外科手术为主,随着现代医疗技术的发展,手术方式呈现多样化,腹腔镜、胆肠吻合术、精准肝部分切除术、肝脏移植、微创取石等各种技术的飞速发展,极大地降低了患者痛苦,但因其术后高复发率、多并发症,严重影响患者的生活质量。目前肝内胆管结石术后复发机制尚未完全清楚,与胆道感染、胆汁淤积、饮食结构等多种因素密切相关。该文就肝内胆管结石术后复发的病因及其危险因素的研究进展进行综述,以期为临床治疗肝内胆管结石及预防术后复发提供一定的帮助。

Intrahepatic bile duct stones(IBDS)is a common disease in clinical hepatobiliary surgery,which is an important cause of death for benign biliary diseases in our country.Its treatment method is dominated by operation,with the development of modern medical technology,the surgical methods are diversified.The rapid development of laparoscopy,choledochojejunostomy,precise partial hepatectomy,liver transplantation,minimally invasive stone extraction and other technologies greatly reduce the pain of the patients.However,due to its postoperative high recurrence rate and multiple complications,the quality of life of the patients is seriously affected.At present,the recurrence mechanism of intrahepatic cholelithiasis has not been fully understood,and is closely related to many factors such as biliary tract infection,cholestasis and dietary structure.In this paper,the etiology and risk factors of recurrence of intrahepatic cholelithiasis are reviewed in order to provide some help for clinical treatment of intrahepatic cholelithiasis and prevention of postoperative recurrence.