456nm半导体蓝激光眩目效应研究

Study on the dazzle effect of 456nm blue laser

为了探讨蓝激光眩目效应量效关系,利用视网膜电流图研究456nm半导体蓝激光照射兔眼的眩目效应,通过视网膜电流图b波振幅恢复时间评价蓝激光致眩效果,绘制剂量-恢复时间曲线,并通过眼底照相机观察激光辐照后的视网膜损伤情况。结果表明,456nm蓝激光眩目效果明显,视网膜电流图b波振幅的恢复时间随蓝激光辐照剂量的增加而延长,恢复时间与剂量间呈良好的线性关系,辐照后即刻和辐照24h后观察眼底未见损伤。本研究将为蓝激光的眩目应用提供了参考。

In order to explore the dose effect relationship of blue laser dazzle effect,electroretinogram was used to evaluate the dazzle effect of a 456nm semiconductor blue laser on rabbit eyes.The dazzle effect of blue laser and its characteristics were evaluated by the recovery time of electroretinogram b-wave amplitude,the dazzling recovery time curves corresponding to different doses were drawn,and the damage of retina after laser irradiation was observed with fundus camera.The results show that the recovery time of b-wave amplitude of electroretinogram(ERG)is prolonged with the increase of laser irradiation dose,and there is a good linear relationship between the recovery time and the dose.No damage is found in the fundus immediately after irradiation and 24h later.This study will provide reference value for the application of blue laser dazzle.