立体选择性烯烃复分解反应的研究及应用

Study and Applications of Stereoselective Olefin Metathesis Reactions

烯烃复分解反应是基于钌卡宾催化的形成碳碳双键的重要反应之一,近年来关于立体选择性烯烃复分解反应的研究越来越多.综述了近年来基于钌催化的立体选择性烯烃复分解反应,包括金属钌催化剂的种类、演化、立体选择性研究进展及其在不对称合成中的应用.重点介绍了近十年来钌催化烯烃复分解反应类型及其在不对称合成中的应用研究进展,并对今后的发展做出展望.

Olefin metathesis has been one of the most important methods to construct carbon-carbon double bonds,which has been catalyzed by ruthenium carbene.Investigations in olefin metathesis have focused on stereoselective transformations in recent years.The research progress on the applications of stereoselective olefin metathesis reactions catalyzed by ruthenium carbene complexes is reviewed.The advancements in stereoselectivity of olefin metathesis are described in detail,and the categories and improvement of ruthenium catalysts are also introduced over the past decade.Finally,the future development for olefin metathesis is further evaluated as well.