分析药学干预对2型糖尿病患者用药依从性及药品不良反应的影响

Influence of pharmaceutical intervention on medication compliance and adverse drug reactions in patients with type 2 diabetes mellitus

目的分析2型糖尿病患者采取药学干预对用药依从性及药品不良反应的影响。方法80例2型糖尿病患者,由随机双盲法分为对照组与观察组,各40例。对照组采取常规护理,观察组采取药学干预。对比两组患者各项血糖指标、用药依从性及药品不良反应发生情况。结果观察组空腹血糖、餐后2 h血糖及糖化血红蛋白分别为(6.12±1.18)mmol/L、(7.52±1.84)mmol/L、(6.57±1.59)%,均低于对照组的(8.37±1.53)mmol/L、(9.66±1.90)mmol/L、(8.58±1.64)%,差异均具有统计学意义(P<0.05)。观察组用药依从率与药品不良反应发生率分别为95.00%、2.50%均优于对照组的80.00%、17.50%,差异均具有统计学意义(P<0.05)。结论2型糖尿病患者采取药学干预,可稳定患者血糖水平,降低药品不良反应发生率,提升患者用药依从性,值得临床实践。

Objective To analyze the influence of pharmaceutical intervention on medication compliance and adverse drug reactions in patients with type 2 diabetes mellitus.Methods A total of 80 patients with type 2 diabetes mellitus were divided into control group and observation group according to random double-blind method,with 40 cases in each group.The control group received routine nursing,and the observation group received pharmaceutical intervention.The blood glucose index,medication compliance and occurrence of adverse drug reactions were compared between the two groups.Results The fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin of the observation group were(6.12±1.18)mmol/L,(7.52±1.84)mmol/L and(6.57±1.59)%,which were lower than(8.37±1.53)mmol/L,(9.66±1.90)mmol/L and(8.58±1.64)%of the control group,and the difference was statistically significant(P<0.05).The medication compliance rate and incidence of adverse drug reactions of the observation group were 95.00%and 2.50%,which were better than 80.00%and 17.50%of the control group,and the difference was statistically significant(P<0.05).Conclusion Pharmaceutical intervention in patients with type 2 diabetes mellitus can stabilize the blood glucose level,reduce the incidence of adverse drug reactions,and improve the medication compliance of patients,which is worthy of clinical practice.