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Ⅰ期、Ⅱ期胰腺导管腺癌根治术后血清CA125、CEA、CA19-9及预后分析

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摘要 目的研究Ⅰ期、Ⅱ期胰腺导管腺癌根治术后患者血清CA125、CEA、CA19-9水平及预后分析,为患者的诊断提供临床指导。方法选取2017年2月至2020年3月期间在本院行胰腺导管腺癌根治术的60例Ⅰ期、Ⅱ期患者作为研究对象。随机分为对照组和观察组,各30例,检测所有患者血清癌抗原125(CA125)、癌胚抗原(CEA)、糖链抗原19-9(CA19-9)水平,探究这三种标志物对胰腺癌的诊断和预后价值。结果术后3种标志物CA19-9、CA125、CEA的水平和阳性率显著低于术前,差异有统计学意义(P<0.05);三种标志物CA19-9、CA125、CEA联合的诊断性显著高于各单一指标组,CA19-9的特异性、敏感性、准确性显著高于CA125和CEA,CEA的诊断性显著高于CA125,差异有统计学意义(P<0.05)。结论CA125和CEA的检测水平对胰腺癌的诊断和预后有一定的辅助作用,联合CA19-9三种指标水平诊断和预后效果更好。
出处 《浙江创伤外科》 2020年第5期952-953,共2页 Zhejiang Journal of Traumatic Surgery
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  • 1杨红,钱家鸣,张惠广,郭涛.胰腺癌300例临床特点分析[J].基础医学与临床,2007,27(7):815-818. 被引量:8
  • 2胰腺癌诊治指南[J].中华外科杂志,2007,45(19):1297-1299. 被引量:13
  • 3Siegel R,Ma J,Zou Z,et al.Cancer statistics,2014,CA Cancer J Clin,2014,64(1):9-29.
  • 4National Comprehensive Cancer Network.Clinical Practice Guidelines in Oncology.Pancreatic Adenocarcinoma.Version 2.2014.Available from:http://www.nccn.org/professionals/physician_gls/f_guidelines.asp.
  • 5Tol JAM,Gouma D J,Bassi C,et al.Definition of a standard lymphadenectomy in surgery for pancreatic ductal adenocarcinoma:A consensus statement by the International Study Group on Pancreatic Surgery (ISGPS)[J].Surgery,2014,156(3):591-600.
  • 6Bockhorn M,Uzunoglu FG,Adham M,et al.Borderline resectable pancreatic cancer:A consensus statement by the International Study Group of Pancreatic Surgery (ISGPS).Surgery,2014,155(6):977-988.
  • 7Hartwig W,Vollmer CM,Fingerhut A,et al.Extended pancreatectomy in pancreatic ductal adenocarcinoma:Definition and consensus of the International Study Group for Pancreatic Surgery (ISGPS)[J].Surgery,2014,156 (1):1-14.
  • 8Asbun HJ,Conlon K,Fernandez-Cruz L,et al.When to perform a pancreatoduodenectomy in the absence of positive histology? A consensus statement by the International Study Group of Pancreatic Surgery[J].Surgery,2014,155 (5):887-892.
  • 9Menon KV,Gomez D,Smith AM,et al.Impact of margin status on survival following pancreatoduo-denectomy for cancer:the Leeds Pathology Protocol (LEEPP).HPB (Oxford),2009,11(1):18-24.
  • 10Nimura Y,Nagino M,Takao S,et al.Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas.Long-term results of a Japanese multicenter randomized controlled trial[J].Journal of Hepato-Biliary-Pancreatic Sciences,2012,19 (3):230-241.

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