EEG与SEP对脓毒症相关性脑病患者脑损伤程度评价

Evaluation of EEG and SEP on the Degree of Brain Injury in Patients With Sepsis Related Encephalopathy

目的探讨脑电图(electroencephalogram,EEG)和体感诱发电位(subcortical evoked potentials,SEP)在脓毒症相关性脑病(Sepsis related encephalopathy,SAE)患者脑损伤程度评价中的应用效果。方法选取2018年1月—2020年1月福建医科大学附属协和医院重症医学科收治的30例SAE患者作为研究组,将同期收治的30例无脑病脓毒症患者作为对照组,均入院后接受EEG与SEP监测,根据监测结果评价SAE患者脑损伤程度。结果通过检测,研究组患者的EEG评级为V级18例、IV级6例、III级4例、II级2例,对照组患者分别为II级9例、I级21例,组间差异有统计学意义(P<0.05);研究组SEP检测,异常22例、正常8例,对照组分别为4例、26例,差异有统计学意义(P<0.05)。结论EEG、SEP可对SAE患者的脑损伤严重程度进行有效监测和评价,为临床治疗干预提供依据。

Objective To evaluate the effects of electroencephalography(EEG)and somatosensory evoked potential(SEP)on the evaluation of brain injury in patients with sepsis associated encephalopathy(SAE).Methods 30 SAE patients admitted to the department of critical care medicine of union hospital affiliated to fujian medical university from January 2018 to January 2020 were selected as the research group,and 30 patients without encephalopathy sepsis admitted during the same period were taken as the control group.Results The EEG rating of the research group was grade V in 18 cases,grade IV in 6 cases,grade III in 4 cases,grade II in 2 cases,grade II in 9 cases,grade I in 21 cases in the control group,and the difference between the groups was statistically significant(P<0.05).In the research group,22 cases were abnormal,8 cases were normal,and 4 cases were abnormal,26 cases were normal in the control group,the difference was statistically significant(P<0.05).Conclusion EEG and SEP can effectively monitor and evaluate the severity of brain injury in patients with SAE and provide a basis for clinical intervention.