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凝血-纤溶指标在下肢深静脉血栓中的变化及与疗效的相关性 被引量:1

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摘要 目的探讨凝血-纤溶指标在下肢静脉血栓中的变化及与疗效的相关性。方法2016年12月至2018年1月该院收治的下肢静脉血栓患者50例,均接受溶栓治疗,根据溶栓效果分为再通组34例与未通组16例。比较两组溶栓前与溶栓24小时后,血浆D-二聚体(D-D)、纤维蛋白原(FIB)和纤维蛋白降解产物(FDP)水平,并对各项指标与血栓溶解率进行相关性分析。结果溶栓后两组的D-D、FIB、FDP水平均低于溶栓前,再通组各项指标均低于未通组。Pearson相关分析显示,血浆D-D、FIB、FDP水平与血栓溶解率均呈负相关(P<0.01)。结论下肢静脉血栓患者血浆的凝血-纤溶指标变化与患者再通效果呈明显负相关,可作为疗效评定的标准。
出处 《中国乡村医药》 2020年第16期9-10,共2页
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