心室颤动导管消融治疗进展

Catheter Ablation for Ventricular Fibrillation

心室颤动(室颤)是心脏性猝死的主要原因之一,植入型心律转复除颤器是现阶段心脏性猝死预防的主要措施,然而,植入型心律转复除颤器并不能有效防止室颤的复发,患者仍有遭受电风暴或多次电击的风险。研究表明,导管消融技术成为室颤及心脏性猝死预防和治疗的新方式。早期室颤消融探索主要针对单一触发点的处理,目前针对室颤维持机制及基质改良的研究不断出现,转子消融亦成为行之有效的方法。现就室颤导管消融的临床现状及最新进展做一综述,用于指导临床治疗策略的制定。

Ventricular fibrillation is one of the leading causes of sudden cardiac death,and implantable cardioverter-defibrillator(ICD)is the main measure to prevent sudden cardiac death at the present stage.However,ICD do not prevent the recurrence of ventricular fibrillation effectively,and patients remain at risk of electrical storm or multiple electric shocks.Studies have shown that catheter ablation should be a new approach of prevention and treatment of ventricular fibrillation and sudden cardiac death.Early exploration of this subject was focused on single trigger factor.At present,research on the maintenance mechanism of ventricular fibrillation and substrate improvement has emerged constantly.Rotor ablation is also become an effective method.In this paper,the clinical status and recent progress of catheter ablation of ventricular fibrillation are reviewed to guide the development of clinical treatment strategies.