基于VOSviewer软件的黄芪治疗糖尿病研究文献计量分析

Bibliometric Analysis of Astragalus membranaceus in the Treatment of Diabetes Based on VOSviewer Software

目的:为直观便捷地了解黄芪治疗糖尿病的研究重点提供数据参考。方法 :检索2000年1月1日-2020年6月30日中国知网全文数据库中收录的关于黄芪治疗糖尿病相关文献,采用文献计量学方法,对文献发表数量、发文作者及其研究方向、关键词、研究机构分布情况、来源期刊分布情况、被引频次、基金资助等内容进行统计分析,并使用VOSviewer软件进行可视化展示。结果:共纳入文献2 960篇,文献数量大体呈现增长趋势;发文量最高的作者是辽宁中医药大学的范颖,研究方向主要为黄芪不同有效部位对糖尿病模型动物血清胰岛素、脂联素的影响等;关键词词频中,糖尿病肾病(845次)、黄芪(615次)、糖尿病(587次)、黄芪注射液(350次)、糖尿病周围神经病变(303)、补气药(202次)等出现频次较高;发文量超过20篇的机构有10所,其中南京中医药大学发文最多(58篇);《陕西中医》《中国中西医结合肾病杂志》《内蒙古中医药》是发文量较多的期刊;陈国辉等发表的《黄芪的化学成分及药理作用研究进展》被引频次最高,为690次;国家级科研基金(包括国家自然科学基金和国家重点基础研究发展计划等)资助项目较多。结论:我国近20年来黄芪治疗糖尿病研究水平稳步提高,但是文献分布不均衡,高质量核心期刊发文量较少,且相关临床试验相对较少。笔者建议研究人员应从宏观临床疗效、微观药理学、黄芪遗传资源库、中医经典方剂等角度探索黄芪治疗糖尿病的方法和思路。

OBJECTIVE:To provide reference for intuitively and conveniently cognizing the research focus of Astragalus membranaceus in the treatment of diabetes.METHODS:Using the method of bibliometrics,the literatures about the treatment of diabetes by A.membranaceus were retrieved from CNKI full-text database during Jan.1st,2000-Jun.30 th,2020.Bibliometric method was used to statistically analyze the number of articles,authors and their research directions,keywords,distribution of research institutions,source journals,frequency of citations,fund funding,etc.VOSviewer software was used for visual display.RESULTS:A total of 2960 literatures were included,and the number of literatures showed an increasing trend;the author with the most literatures was Fan Ying from Liaoning University of TCM,whose research direction was the effect of different effective parts of A.membranaceus on serum insulin and adiponectin in diabetic animal models;in the keyword frequency analysis,diabetic nephropathy(845 times),A.membranaceus(615 times),diabetes(587 times),A.membranaceus injection(350 times),diabetic peripheral neuropathy(303 times),qi tonifying drug(202 times)were hot topics.There were 10 institutions with more than 20 literatures,of which Nanjing University of TCM has published the most literatures(58 pieces).Shaanxi Journal of Traditional Chinese Medicine,Chinese Journal of Integrated Traditional and Western Nephropathy and Inner Mongolia Journal of Traditional Chinese Medicine were the journals with a large number of literatures;Research Progress on Chemical Constituents and Pharmacological Effects of Astragalus membranaceus published from Chen guohui and others was cited most frequently,for 690 times;there are many projects funded by national scientific research funds(including National Natural Science Foundation of China and the National Key Basic Research Special Foundation of China).CONCLUSIONS:In the past 20 years,the level of researches about A.membranaceus in the treatment of diabetes have been steadily improved.However,the distribution of literature is uneven and there are few high-quality core journals.Mainly,there are relatively few clinical trials.It is suggested that researchers should explore the methods and ideas of A.membranaceus in the treatment of diabetes from the perspectives of macro clinical efficacy,micro pharmacology,A.membranaceus genetic resource bank and traditional Chinese medicine formulations.