开窗减压术治疗口腔颌面部囊肿的效果

Effect of Fenestration Decompression on Oral and Maxillofacial Cyst

目的研究开窗减压术对口腔颌面部囊肿的临床效果。方法选取2018年8月~2019年8月在我院诊治的92例口腔颌面部囊肿患者为研究对象,采用随机数字表法分为对照组和观察组,各46例。对照组采用常规囊肿刮除术,观察组采用开窗减压术治疗,比较两组治疗总有效率、手术指标(手术时间、术中出血量)、免疫功能指标(CD3^+T、CD4^+T、CD8^+T、NK、CD4^+/CD8^+)、并发症发生率及复发率。结果观察组治疗总有效率为95.65%,高于对照组的80.43%(P<0.05);观察组手术时间、术中出血量均小于对照组(P<0.05);治疗后观察组CD3^+T细胞百分比与对照组比较,差异无统计学意义(P>0.05),CD4^+T、CD4^+/CD8^+细胞百分比均低于对照组,CD8^+T、NK细胞百分比均高于对照组(P<0.05);观察组并发症发生率低于对照组(P<0.05);随访4个月,观察组复发率低于对照组(P<0.05)。结论开窗减压术对口腔颌面部囊肿效果确切,总有效率高,且可改善患者免疫功能,减少并发症及复发情况的发生,值得应用。

Objective To study the clinical effect of fenestration decompression on oral and maxillofacial cysts.Methods A total of 92 patients with oral and maxillofacial cysts who were diagnosed and treated in our hospital from August 2018 to August 2019 were selected as the research objects.They were divided into control group and observation group by random number table method,with 46 cases in each group.The control group was treated with conventional cyst curettage,and the observation group was treated with fenestration decompression.The two groups were compared with the total effective rate of treatment,surgical indexes(operation time,intraoperative blood loss),immune function indexes(CD3^+T,CD4^+T,CD8^+T,NK,CD4^+/CD8^+),complication rate and recurrence rate.Results The total effective rate of treatment in the observation group was 95.65%,which was higher than 80.43%in the control group(P<0.05);the operation time and intraoperative blood loss in the observation group were less than those in the control group(P<0.05);After treatment,the percentage of CD3^+T cells in the observation group was not statistically different from that in the control group(P>0.05).The percentages of CD4^+T and CD4^+/CD8^+cells were lower than those in the control group.CD8^+T and NK cells The percentages were higher than those of the control group(P<0.05);the incidence of complications in the observation group was lower than that of the control group(P<0.05);the observation group was followed up for 4 months,and the recurrence rate in the observation group was low In the control group(P<0.05).Conclusion Fenestration decompression had a definite effect on oral and maxillofacial cysts,and the total effective rate was high.It could improve the patient's immune function and reduce the occurrence of complications and recurrence.It was worthy of application.