Therapeutic efficacy observation on moxibustion with moxa of different storage years for moderate-to-severe primary knee osteoarthritis

不同储存年份艾绒灸治中重度原发性膝骨关节炎疗效观察

Objective:By observing the differences in Western Ontario and McMaster Universities osteoarthritis index(WOMAC)and visual analog scale(VAS)scores in moxibustion treatment for moderate-to-severe primary knee osteoarthritis(KOA)with moxa of different storage years(3-year moxa and 1-year moxa from Qichun,Huanggang City,Hubei Province,China)through a randomized clinical trial,to objectively evaluate the differences in therapeutic efficacy of moxibustion with moxa of different storage years.Methods:A total of 63 patients with moderate-to-severe KOA who met the inclusion criteria were randomized into moxibustion group 1 and moxibustion group 2 by central randomization method,with 32 cases in moxibustion group 1 and 31 cases in moxibustion group 2.Moxibustion group 1 was treated with moxa stored for 3 years,and moxibustion group 2 was treated with moxa stored for 1 year.Dubi(ST 35),Neixiyan(EX-LE 4)and Heding(EX-LE 2)were selected in both groups,and the treatment lasted 20 min per time,3 times a week.The immediate efficacy was compared after 6 times of treatment,and long-term efficacy was compared at follow-up 4 weeks after the end of treatment.Results:During the treatment,there were 2 dropouts in moxibustion group 1,and 1 dropout in moxibustion group 2.The total effective rate in the two groups was 83.3%and 60.0%,respectively.Followed up at 4 weeks after the end of treatment,the total effective rate in the two groups was 80.0%and 66.7%,respectively.There were no statistical differences between the two groups(both P>0.05).After treatment and 4 weeks after the end of treatment,the WOMAC and VAS scores in both groups decreased significantly compared with those before treatment(all P<0.01);the scores of stiffness item of WOMAC in moxibustion group 1 were lower than those in moxibustion group 2(both P<0.05);there were no statistical differences in the scores of pain item and dysfunction item of WOMAC,and VAS scores between the two groups(all P>0.05).Conclusion:Moxibustion with moxa of different storage years(stored for 3 years and 1 year)both can improve the pain,stiffness and motor function in patients with moderate-to-severe KOA.While moxa stored for 3 years has a better therapeutic efficacy in improving stiffness of the knee joint than that stored for 1 year.

目的:通过临床随机对照试验,观察不同储存年份(湖北省黄冈市蕲春的3年艾绒和1年艾绒)的艾绒灸治中重度膝骨关节炎的西安大略与麦克马斯特大学骨关节炎指数(WOMAC)和视觉模拟量表(VAS)评分,客观评价不同储存时间艾绒灸治的疗效差异.方法:将63例符合纳入标准的中重度膝骨关节炎患者采用中央随机法分为艾灸1组32例和艾灸2组31例.艾灸1组采用储存3年的艾绒灸治,艾灸2组采用储存时间1年的艾绒灸治,两组均取犊鼻、内膝眼和鹤顶,每次治疗20 min,每周3次.于治疗6次后比较两组即刻疗效,于治疗结束4周后随访比较远期疗效.结果:治疗过程中,艾灸1组脱落2例,艾灸2组脱落1例.两组治疗结束时的总有效率分别为83.3%和60.0%,治疗结束4周后随访时的总有效率分别为80.0%和66.7%,两组间均无统计学差异(均P>0.05).治疗结束时及治疗结束4周后随访时两组WOMAC及VAS评分均较治疗前明显下降(均P<0.01);艾灸1组WOMAC僵硬项目评分均低于艾灸2组(均P<0.05);两组间WOMAC疼痛项目及功能障碍项目评分以及VAS评分均无统计学差异(均P>0.05).结论:不同储存时间(储存3年和储存1年)的艾绒灸治均能显著改善中重度膝骨关节炎患者的疼痛、僵硬和活动功能;储存3年的艾绒灸治在改善膝关节僵硬方面的疗效优于储存1年的艾绒灸.