摘要
目的:探讨慢性荨麻疹的发生与患者血清25-羟基维生素D3水平的关系。方法:采用酶联免疫吸附法(ELISA)对长治市第二人民医院门诊2018年2月至12月接诊的236例慢性荨麻疹患者(作为慢性荨麻疹组)和同期在该院接受体检的120例健康体检者(作为对照组)进行血清25-羟基维生素D3检测,然后比较两组人员血清25-羟基维生素D3的水平及其中维生素D缺乏者的占比。结果:1)慢性荨麻疹组患者血清25-羟基维生素D3的水平〔(42.35±3.52)nmol/L〕低于对照组体检者血清25-羟基维生素D3的水平〔(78.53±6.71)nmol/L〕,P<0.05。2)慢性荨麻疹组患者中维生素D缺乏者的占比(77.9%)高于对照组体检者中维生素D缺乏者的占比(51.7%),P<0.05。结论:慢性荨麻疹的发生与患者血清25-羟基维生素D3的水平较低密切相关。
Objective:To investigate the relationship between the occurrence of chronic urticaria and the serum level of 25-hydroxyvitamin D3.Methods:enzymelinked immunosorbent(ELISA)in changzhi city second people’s hospital outpatient service in February 2018 to December,accepts the 236 cases of patients with chronic urticaria(as chronic urticaria group)and in the same period in the healthy check-up of the 120 cases of medical examination at the hospital(as control)is used to detect the serum 25-hydroxy vitamin D3,then compared the two groups the levels of serum 25-hydroxy vitamin D3 and vitamin D deficiency in proportion.Results:1)The serum level of 25-hydroxyvitamin D3((42.35±3.52)nmol/L)in patients with chronic urticaria was lower than that in the control group((78.53±6.71)nmol/L),P<0.05.2)The proportion of patients with vitamin D deficiency in the chronic urticaria group(77.9%)was higher than that in the control group(51.7%),P<0.05.Conclusion:The occurrence of chronic urticaria is closely related to the low serum level of 25-hydroxyvitamin D 3.
作者
李慧
Li hui(Dermatology Department,The Second People’s Hospital of Changzhi,Changzhi 046000)
