角膜神经性疼痛诊治进展

Detection and the current feasible treatment of neuropathic corneal pain

角膜神经性疼痛是一种定义不明的疾病。针对角膜神经性疼痛患者的临床建议、检测方法和治疗方法十分缺乏。目前基于对神经性疼痛病理生理学上的研究,临床上已有一些可行的检测方法和治疗方法,其中检测方法包括使用活性染料的裂隙灯检查法、触觉测量计、丙美卡因挑战测试法、体内共焦距显微镜检测。治疗方法包括抗炎症疗法、神经再生性疗法、系统用药、使用保护性隐形眼镜和一些辅助疗法。本文旨在总结针对其可行的检测方法和治疗方法。

Neuropathic corneal pain is an ill-defined illness.Clinical recommendations and treatments for patients are scarce.Nowadays,based on researches of the pathophysiology of neuropathic pain,there are some feasible methods for detection and treatments including slit lamp inspection using reactive dyes,tactile meters,proparacaine challenge test,and in vivo confocal microscopy,as well as anti-inflammation therapy,neuro-regenerative therapy,systemic pharmacotherapy,using protective contact lenses,pharmcotherapeutic strategies and some adjuvant therapies.This review summarizes some current feasible detection methods and treatments.