徐长卿的化学成分、药理作用及质量控制研究进展

Research progress on chemical constituents,pharmacological activities,and quality control of Cynanchum paniculatum

徐长卿(Cynanchum paniculatum)是我国传统中药,临床上主要用于治疗风湿疼痛、湿疹、顽癣、荨麻疹、毒蛇咬伤等疾病。当前研究表明,徐长卿提取物富含饱和烃类、挥发油、苯乙酮类、五环三萜类、C21甾体类、生物碱、多糖、甾醇等化合物,具有抗菌、抗病毒、保护心血管、免疫调节、抗肿瘤等作用。综述徐长卿的化学成分、药理作用和质量控制研究,将为徐长卿及其相关产品的开发提供参考。

Cynanchum paniculatum(Bge.)Kitag(designed as CPBK)as traditional Chinese medicine is commonly used to treat rheumatic pain,eczema,stubborn ringworm,urticarial and snake bites.The CPBK contains a great kinds of secondary metabolits,such as saturated hydrocarbons,volatile oils,acetophenones,pentacyclic triterpenes,C21 steroids,alkaloids,polysaccharides,sterols and other compounds.The components of CPBK extract exhibited obviousantibacterial,antiviral,cardiovascular protection,immune regulation and anti-tumor activities.This article reviewed chemical constituents,pharmacological activities and quality control about Cynanchum paniculatum,which would offer valuable materals for future study.