摘要
Blue nevus(BN)is a benign,acquired pigmented lesion characterized by a bluish or dark-bluish pigmentation.Most lesions are benign and stable over time,sometimes developing into malignant blue nevus(MBN),a variant of malignant melanoma.The prognosis in MBN is at least as serious as in conventional melanoma.[1]Additionally,a differential diagnosis of BN including nodular melanoma,pigmented basal cell carcinoma,and cutaneous metastasis of melanoma may lead to excessive surgical excisions.
基金
This work was supported by the Fundamental Research Funds for the Central Universities(No.3332019163)
Beijing Municipal Science and Technology Commission Medicine Collaborative Science,and Technology Innovation Research Project(No.Z191100007719001)。