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1例儿童造血干细胞移植术后并发淋巴细胞增生性疾病的护理 被引量:2

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摘要 造血干细胞移植术(hematopoietic stem cell transplantation HSCT)是白血病、淋巴瘤、多发性骨髓瘤、骨髓增生异常综合征、免疫缺陷病、先天性疾病等多种疾病治疗的重要手段[1]。HSCT常见并发症包括:感染、移植物抗宿主病、巨细胞病毒及相关性间质性肺炎、HSCT后肝静脉阻塞病等[2]。移植后淋巴细胞增殖性疾病(Posttransplantation Lymphoproliferative disorders PTLD)是造血干细胞移植及实体器官移植后患者由于免疫抑制而发生的一组良性淋巴组织增殖到恶性肿瘤的淋巴系统增殖性疾病[3]。
作者 刘丽萍 杨凡
出处 《当代护士(中旬刊)》 2020年第11期167-168,共2页 Modern Nurse
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  • 5Pfreundschuh M,Truemper L,Osterborg A,et al.CHOP-like chemotherapy plus fituximab versus CHOP-like chemotherapyalone in young patients with good-prognosis diffuse large-B- celllymphoma : a randomised controlled trial by the MabThera International TriM(MinT)Group. Lancet Oncol, 2006,7(5):379-391.
  • 6Bienvenu J, Chvetzoff R, Salles G, et al. Tumor necrosis factor arelease is a major biologicalevent associated with rituximab treatment. Hematol J, 2001,2(6):378-384.
  • 7Loren AW,Porter DL,Stadtmauer EA. Post-transplant lymphoproliferative disorder:a review[J].Bone Marrow Transplantation,2003,(03):145-155.doi:10.1038/sj.bmt.1703806.
  • 8Sundin M,Le Blanc K,Ringdén O. The role of HLA mismatch,splenectomy and recipient Epstein-Barr virus seronegativity as risk factors in post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation[J].Haematologica,2006,(08):1059-1067.
  • 9Novoa-Takara L,Perkins SL,Qi D. Histogenetic phenotypes of B cells in posttransplant lymphoproliferative disorders by immunohistochemical analysis correlate with transplant type:solid organ vs hematopoietic stem cell transplantation[J].American Journal of Clinical Pathology,2005,(01):104-112.
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