Yang xin shi tablet enhances adaptability to exercise training by relieving statin-induced skeletal muscle injury

To the Editor:Widely used statins lower the risk of death from cardiovascular diseases.However,statin-associated skeletal muscle complaints hinder their clinical application to some extent.Yang xin shi tablet(YXST),a traditional Chinese medicine formula,can effectively improve the clinical symptoms of patients with cardiovascular diseases when combined with conventional drugs.However,the synergistic effects of YXST combined with a statin and the potential mechanisms remain unknown.Hence,exploring the effects and mechanisms of YXST in improving statin-induced muscle injury can be beneficial for the exercise rehabilitation and prognosis of patients with cardiovascular disease.