经皮射频热凝治疗原发性三叉神经痛的预后影响因素分析

Analysis of clinical characteristics and prognosis in patients with primary trigeminal neuralgia under percutaneous radiofrequency thermocoagulation

目的:总结原发性三叉神经痛(PTN)的临床特点,探讨经皮射频热凝术治疗PTN预后的影响因素。方法:回顾分析2017年1月~2019年12月于中日友好医院疼痛科行经皮射频热凝手术的70例PTN患者的临床资料,对影响术后是否复发和是否有并发症的临床因素进行统计分析。结果:本组PTN患者平均发病年龄66岁,发病率女性稍高于男性(1.1:1)、三叉神经第二支和第三支发病高于第一支。与外周支射频热凝相比,半月神经节射频热凝术后并发症的风险明显增加(OR=4.286,95%CI 1.354~13.561),且射频热凝部位(OR=7.517,95%CI1.725~32.760)和BMI(OR=1.346,95%CI 1.079~1.678)是术后发生面部麻木的独立危险因素。结论:射频热凝部位可能是影响PTN患者术后并发症的独立危险因素。射频热凝部位和BMI可能是影响患者术后面部麻木的独立危险因素。

Objective:To summarize the clinical characteristics of primary trigeminal neuralgia and to explore the risk factors affecting the prognosis of percutaneous radiofrequency thermocoagulation.Methods:Clinical data of 70 patients with primary trigeminal neuralgia who underwent percutaneous radiofrequency thermocoagulation in the Department of Pain Medicine of China-Japan Friendship Hospital from January 2017 to December2019 were retrospectively analyzed.Results:The average age of onset of primary trigeminal neuralgia was 66 years.The incidence of trigeminal neuralgia was slightly higher in females than in males(1.1:1).Both univariate and multivariate analysis revealed that the site of radiofrequency thermocoagulation was the significant risk factor of postoperative complications(OR=4.286,95%CI 1.354~13.561)and the site of radiofrequency thermocoagulation(OR=7.517,95%CI 1.725~32.760)and BMI(OR=1.346,95%CI 1.079~1.678)were the independent risk factors of postoperative facial numbness.Conclusion:The site of radiofrequency thermocoagulation is one of the independent risk factors for postoperative complications.The site of radiofrequency thermocoagulation and BMI maybe were the independent risk factors for postoperative facial numbness.