细菌生物膜与各微生物类群之间的作用关系

Study on the relationship between bacterial biofilm and various microbial taxa

从细菌生物膜与真菌、其他细菌、原生动物及噬菌体4个角度对其作用进行了综述。在细菌与真菌之间,生物膜不仅是细菌的拮抗手段,也可介导两者之间的共存。在应对异种细菌时,其作为一种物理防御手段与入侵者竞争。遭受原生动物捕食时,生物膜的致密程度上升以应对原生动物的冲击,或是减少生物膜形成,形成不易被掠食的微菌落。而在抵抗噬菌体侵染方面,生物膜的作用包括使菌体紧密排列,调节本身化学成分变化及群体感应功能,抑制噬菌体感染。

This paper reviews the effects on bacterial biofilms from perspectives of fungi,other bacteria,protozoa and bacteriophages.Between bacteria and fungi,the biofilms are not only means of antagonism of bacteria,but also intermediate coexistence of the two.When dealing with heterogeneous bacteria,it competes with intruders as a physical defender.When it suffers from predator’s predation the density of biofilms increased to cope with the impact of protozoa,or the formation of biofilms reduced and then the uneasily predated microcolonies formed.In terms of resistance to bacteriophage’s infection,the role of biofilms includes aligning the bacteria closer,regulating their chemical composition and their quorum sensing,to inhibit bacteriophage infection.