期刊文献+

阿司匹林和低分子肝素治疗习惯性流产的临床疗效评价 被引量:8

Clinical evaluation of aspirin and low molecular weight heparin in the treatment of habitual abortion
下载PDF
导出
摘要 目的分析针对习惯性流产患者,阿司匹林联合低分子肝素的治疗效果。方法选取2017年2月至2019年6月在本院接受治疗的习惯性流产患者100例作为研究对象,依照随机分配的方式分为实验组与对照组,每组50例。对照组患者采用阿司匹林开展治疗,实验组患者采用阿司匹林联合低分子肝素开展治疗,治疗后,对比两组患者流产率、足月产率、活产率、不良反应发生率以及分娩孕周。结果实验组足月产率以及活产率分别为76.0%与96.0%,高于对照组的54.0%与84.0%,差异有统计学意义(P<0.05);实验组分娩孕周时长为(39.14±2.01)周长于对照组的(37.25±1.04)周,差异有统计学意义(P<0.05);实验组不良反应发生率为6.0%,低于对照组的20.0%,差异有统计学意义(P<0.05)。结论阿司匹林联合低分子肝素治疗效果显著,具有临床推广价值。 Objective To analyze the treatment effect of aspirin and low molecular weight heparin on habitual abortion patients.Methods 100 cases patients with habitual abortion from February 2017 to June 2019 who came to our hospital for treatment were selected as the study subjects.According to the way of random distribution,the patients were divided into experimental group and control group,with 50 cases in each group.The control group was used Aspirin to treat the patients,the experimental group was used aspirin combined with low molecular weight heparin to treat the patients.After the treatment,the abortion rate,full-term rate,live birth rate and pregnancy week of delivery were compared between the two groups.Results The full-term rate and live rate of the experimental group were 76.0%and 96.0%,respectively,which were higher than that of the control group(54.0%and 84.0%),and the data difference between the groups was significant(P<0.05).The gestational age of the experimental group was(39.14±2.01)weeks,which was longer than that of the control group(37.25±1.04)weeks,and the difference between the two groups was significant(P<0.05).The adverse reaction rate of the experimental group was 6.0%,which was lower than that of the control group(20.0%),and the difference between the two groups was significant(P<0.05).Conclusion Aspirin combined with low-molecular-weight heparin is more effective and has clinical promotion value.
作者 邱文芳 温泉 刘素梅 Qiu Wenfang;Wen Quan;Liu Sumei(Department of Gynecology,Ganzhou Maternal and Child Health Hospital,Ganzhou,Jiangxi,341000,China)
出处 《当代医学》 2020年第32期20-22,共3页 Contemporary Medicine
关键词 阿司匹林 低分子肝素 习惯性流产 临床疗效 Aspirin Low molecular weight heparin Habitual abortion Clinical efficacy
  • 相关文献

参考文献11

二级参考文献56

  • 1周学平.低分子肝素治疗急性脑梗死的临床研究[J].临床和实验医学杂志,2006,5(4):354-354. 被引量:9
  • 2脑卒中患者临床神经功能缺损程度评分标准(1995)[J].中华神经科杂志,1996,29(6):381-383. 被引量:15736
  • 3陈清堂.临床神经病学[M].北京:北京科学技术出版社,2004:198-212.
  • 4Pratip C,Sayani B,Piyali S,et al. Aspirin and low- molecular weight heparin combination therapy effectivelyprevents recurrent miscarriage in hyperhomocysteinemic women[J]. Plos One, 2013,8 (9) : 741-745.
  • 5Fouda UM,Sayed AM,Ramadan DI,et al. Efficacy and safety of two doses of low molecular weight heparin (enoxaparin) in pregnant women with a history of recur- rent abortion secondary to antiphospholipid syndrome [J]. Journal of Obstetrics and Gynaecology, 2010,30 (8) : 842- 846.
  • 6De Vries JIP,Van Pampus MG,Hague WM,et al. Low- molecular-weight heparin added to aspirin in the preven- tion of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia:The FRUIT-RCT[J]. Journal of Thrombosis and Haemostasis, 2012,10 ( I ) : 64-72.
  • 7全国第四次脑血管病学术会议.脑血管病分类?诊断要点?腑卒中患者临床冲经功能缺损程度评分标准[J].中华神经科杂志,1996,29(6):379.
  • 8Crosignani PG, Rubin BL. Recurrent spontaneous a- bortion[J]. Hum Reprod,1991,6(4) :609 - 610.
  • 9Derksen RH, de Groot PG. The obstetric antiphos- pholipid syndrome[J]. Journal of Reproductive Im- munology,2007, 77(1) : 41 - 50.
  • 10Sheppard BL, Bonnar. Uteroplacental hemostasis in intrauterine fetal growth retardation [ J ]. Semin Thromb Hemost, 1999, 25 (5) :443-446.

共引文献156

同被引文献95

引证文献8

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部