早期运用丹参酮ⅡA磺酸钠注射液治疗急性脑梗死的疗效和对神经功能的影响

Effect of early application of sodium tanshinone Ⅱ A sulfonate injection on curative effect and neurological function in patients with acute cerebral infarction

目的探讨早期运用丹参酮ⅡA磺酸钠注射液治疗急性脑梗塞的疗效和对神经功能的影响。方法选取2018年4月至2019年5月本院收治的60例急性脑梗死患者,采取随机数字表法分为对照组与观察组,各30例。对照组采取常规治疗,观察组采取丹参酮ⅡA磺酸钠注射液治疗,观察比较两组临床疗效、治疗前后神经功能缺损评分及血清D-二聚体水平。结果观察组有效率为93.33%,明显高于对照组的70.00%,差异有统计学意义(P<0.05);治疗后,观察组神经功能缺损评分、血清D-二聚体水平均低于对照组,差异有统计学意义(P<0.05)。结论急性脑梗塞患者早期运用丹参酮ⅡA磺酸钠注射液治疗能够有效改善患者神经功能,降低血清D-二聚体水平,临床效果显著,值得临床推广。

Objective To investigate the clinical efficacy and safety of tanshinone Ⅱ A sodium sulfonate injection in the early treatment of acute cerebral infarction.Methods 60 patients with acute cerebral infarction admitted to our hospital from April 2018 to May 2019 were divided into control groups and observation group by random number table,with 30 cases in each group.The control group was treated by routine treatment,while the observation group was treated by sodium tanshinone Ⅱ A sulfonate injection.The clinical efficacy,neurological deficit score and serum D-mimer were observed and compared between the two groups before and after treatment.Results The effective rate of the observation group(93.33%)was significantly higher than the control group(70.00%)(P<0.05).After treatment,the neurological deficit score and serum D-dimer level of the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).Conclusion Early application of sodium tanshinone Ⅱ A sulfonate injection in patients with acute cerebral infarction can effectively improve the neurological function of patients and reduce the level of serum D-dimer.The clinical effect is remarkable,which is worthy of clinical promotion.