摘要
目的:建立电感耦合等离子体质谱法(ICP-MS)同时测定玉叶金花中16种重金属元素。方法:采用微波消解法联合ICP-MS法,以钪、锗、铑、铟、铋为内标元素,采用KED模式对样品中重金属元素的含量进行测定。结果:16种重金属元素具有良好的线性关系,线性系数(r)均大于0.9992,重复性测试RSD小于2.5%,精密度测试RSD为0.91%~3.7%,回收率为85.6%~109.4%。结论:该方法准确度高,重复性好,灵敏度强,操作简便,可为玉叶金花中重金属的测定与控制提供参考依据。
Objective:To establish a method for the determination of 16 heavy metal elements in Mussaenda pubescens Ait.f.by inductively coupled plasma mass spectrometry(ICP-MS).Methods:The microwave digestion combined with ICP-MS was used with Sc,Ge,Rh,In and Bi as the internal standard elements,and KED pattern was used to determine the contents of heavy metal elements.Results:Totally 16 heavy metal elements all had a good linear relationship and the linear coefficients(r)were greater than 0.9992.The RSDs for repeatability test were less than 2.5%,and those for precision test were 0.91%-3.7%,and the recoveries were between 85.6%and 109.4%.Conclusion:The method has high accuracy,good repeatability,high sensitivity and simple operation,which can provide reference for the determination and control of heavy metal elements in Mussaenda pubescens Ait.f.
作者
楚浩
符春花
申磊
吴泽君
Chu Hao;Fu Chunhua;Shen Lei;Wu Zejun(Zhuzhou Institute for Food and Drug Control,Hunan Zhuzhou 412000,China)
出处
《中国药师》
CAS
2020年第10期2068-2071,共4页
China Pharmacist