基于多学科协作对AECOPD患者药物治疗管理的效果评价

Efficacy Evaluation of MTM for AECOPD Patients Based on MDT

目的:评价基于多学科协作(MDT)对慢性阻塞性肺疾病急性加重期(AECOPD)患者药物治疗管理(MTM)的效果。方法:AECOPD住院患者323例随机分为试验组(n=165)和对照组(n=158)。对照组患者给予常规治疗;试验组患者给予MDT模式下的MTM。比较两组患者住院期间的药品不良反应发生情况、抗菌药物使用强度、住院天数、住院总费用和满意度;以及出院1个月后的用药依从性评分、CAT评分及吸入剂的使用合理性评分变化。结果:住院期间试验组患者的不良反应发生次数、抗菌药物使用强度、住院天数、住院总费用以及满意度等指标均优于对照组(P<0.05)。两组患者出院1个月后的用药依从性、CAT及吸入剂使用评分均较入院时明显改善(P<0.05),且试验组上述指标评分均显著优于对照组(P<0.05)。结论:对AECOPD住院患者提供MDT模式下的MTM,有利于提高药学服务质量和临床疗效。

Objective: To evaluate the efficacy of medication therapy management(MTM) for AECOPD patients based on multi-disciplinary team(MDT). Methods:A total of 323 inpatients with AECOPD were divided into experimental group(n=165) and control group(n=158) at random. Patients in the control group were given conventional treatment, while patients in the experimental group provided MTM in a MDT mode. The occurrence of adverse drug reactions, intensity of antibacterial drug use, length of stay, total cost of hospitalization, and satisfaction were compared between the two groups during hospitalization. After intervention, medication compliance score, CAT score and inhalant use score were compared between the two groups one month after discharge from hospital. Results:During the hospitalization period, the number of adverse reactions, the intensity of antimicrobial use, the length of stay, the total cost of hospitalization, and the degree of satisfaction in the experimented group were all better than those of the control group(P<0.05). After intervention, the medication compliance, CAT and inhalant use scores of patients in both groups one month after discharge were improved compared with those before intervention(P<0.05), and the scores of the above three indicators in the experimental group were significantly better than those in the control group(P<0.05). Conclusion:Providing MTM in MDT mode for inpatients with AECOPD is beneficial to improving the quality of pharmacy services and clinical efficacy for inpatients with AECOPD.