海藻抗肿瘤活性肽的研究进展

Research progress on antitumor active peptides derived from seaweed

肿瘤是人类健康安全的严重威胁,发病率和死亡率逐年攀升。近年来,天然海藻成为获取高效、低毒副作用的生物活性肽的海洋生物来源之一,海藻源活性肽的抗肿瘤活性逐渐为研究人员所关注。文中综述了海藻活性肽的常见种类和常用制备方法,同时对海藻抗肿瘤活性肽的活性评价方法和作用机制加以阐述,期望为抗肿瘤天然药物和食品的开发提供参考。

Malignant tumor is a serious threat to human health.Its incidence rate and mortality rate are also increased year by year.In recent years,natural seaweeds have been used to obtain bioactive peptides which with high efficiency and low toxicity.Therefore,the antitumor activity of bioactive peptides derived from seaweeds has gradually attracted the attention of researchers.This paper reviewed the common kinds and preparation methods of seaweed bioactive peptides.Meanwhile,the evaluation methods and mechanism of seaweed antitumor active peptides were also been described,so as to provide reference for the development of antitumor natural drugs and foods.