厄贝沙坦联合针灸治疗原发性高血压的临床疗效探究

Exploration on the Clinical Efficacy of Irbesartan Combined with Acupuncture and Moxibustion in the Treatment of Essential Hypertension

目的探究原发性高血压患者使用厄贝沙坦联合针灸治疗的临床效果。方法将2016年12月—2019年8月接收的220例原发性高血压患者按照治疗方式中是否采取中医针灸治疗分为联合组与参照组,每组110例,参照组采用厄贝沙坦,联合组则在参照组的基础上采取中医针灸治疗,对比两组治疗后的血压、不良反应,总结各组的疗效。结果联合组治疗后的SBP(129.68±6.54)、DBP(70.65±8.02)mmHg与参照组(145.38±8.43)、(83.65±6.95)mmHg比较,组间差异有统计学意义(t=8.507、8.019,P=0.021、0.024);两组的心率差异无统计学意义(t=0.842,P=0.949);联合组的总疗效92.73%与参照组67.27%比较,组间差异有统计学意义(χ^2=19.346,P=0.007);联合组出现头晕、头痛、咳嗽等不良反应的发生率4.55%与参照组6.63%差异无统计学意义(χ^2=1.015,P=0.896)。结论对于原发性高血压患者,临床上采取厄贝沙坦联合针灸治疗方式,其疗效更加显著,值得临床推广应用。

Objective To explore the clinical effects of irbesartan combined with acupuncture treatment in patients with essential hypertension.Methods 220 patients with essential hypertension received from December 2016 to August 2019 were divided into a combination group and a reference group of 110 patients according to whether they were treated with traditional Chinese medicine acupuncture and moxibustion.The reference group was treated with irbesartan and combined group took TCM acupuncture treatment on the basis of the reference group,compared the blood pressure and adverse reactions of the two groups after treatment,and summarized the curative effect of each group.Results The SBP(129.68±6.54)mmHg and DBP(70.65±8.02)mmHg of the combined group after treatment were compared with the reference group(145.38±8.43)mmHg and(83.65±6.95)mmHg.The difference between the groups was statistically significant(t=8.507,8.019,P=0.021,0.024);the heart rate difference between the two groups was not statistically significant(t=0.842,P=0.949);the total curative effect of the combination group was 92.73%compared with the reference group 67.27%,the difference between the groups was statistically significant(χ^2=19.346,P=0.007);The incidence of dizziness,headache,cough and other adverse reactions in the combination group was 4.55%and 6.63%in the reference group,the difference was not statistically significant(χ^2=1.015,P=0.896).Conclusion For patients with essential hypertension,irbesartan combined with acupuncture treatment is clinically more effective and worthy of clinical application.