胰高血糖素样肽-1受体激动剂在2型糖尿病心血管并发症中的研究进展

Progress in the Study of GLP-1 Receptor Agonists in Cardiovascular Complications of Type 2 Diabetes Mellitus

在2型糖尿病并发症中,心血管病变是最主要的致死原因。胰高血糖素样肽-1(GLP-1)作为一种新型的糖尿病治疗药物,不仅可在促进胰岛素分泌的同时,抑制胰高血糖素分泌,还能有效改善2型糖尿病心血管并发症。现就GLP-1受体激动剂治疗2型糖尿病心血管并发症的研究进展做一综述。

Among the complications of type 2 diabetes mellitus,cardiovascular disease is the main cause of death.Glucagon-like peptide-1(GLP-1),as a noveltreatment drugfordiabetes,can not only promote insulin secretion,but also inhibit glucagon secretion,and effectively improve cardiovascular complicationsoftype 2 diabetes mellitus.This article reviews the progress of GLP-1 receptor agonists in the treatment of cardiovascular complications oftype 2 diabetes mellitus.