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血清T淋巴细胞亚群及尿MCP-1水平动态检测在系统性红斑狼疮患者病情评估中的价值分析

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摘要 目的研究血清T淋巴细胞亚群及尿单核细胞趋化蛋白-1(MCP-1)水平动态检测在系统性红斑狼疮(SLE)患者病情评估中的应用价值。方法选取我院2018年1月~2019年3月收治的SLE患者72例,按照病情分为活动组和稳定组各36例,取正常健康人36例为对照组,分析不同时期血清T淋巴细胞亚群(CD4^+、CD8^+、CD4^+/CD8^+)、尿MCP-1水平。结果稳定组、活动组CD4^+水平低于对照组,且活动组低于稳定组,差异均有统计学意义(P<0.05);稳定组、活动组CD8^+水平高于对照组,活动组高于稳定组,差异均有统计学意义(P<0.05);活动组、稳定组CD4^+/CD8^+低于对照组,且活动组低于稳定组,差异均有统计学意义(P<0.05);稳定组、活动组尿MCP-1水平高于对照组,活动组高于稳定组,差异均有统计学意义(P<0.05)。结论血清T淋巴细胞亚群、尿MCP-1可作为评估SLE病情的判断依据。
作者 陈小利
出处 《现代诊断与治疗》 CAS 2020年第19期3084-3085,共2页 Modern Diagnosis and Treatment
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