加速康复外科在肝移植中的作用及安全性

Efficacy and safety of enhanced recovery after surgery in liver transplantation

目的了解加速康复外科(ERAS)在肝移植患者中的应用效果和安全性。方法通过“ERAS”或“Fast track”“liver transplantation”等关键词在PubMed、Embase、中国知网等数据库中检索相关文献,检索截止日期为2020年6月3日。对近年来国内外ERAS在肝移植中研究的相关文献进行综述。结果ERAS通过围手术期一系列异于传统管理的措施,能有效促进肝移植患者术后进食、活动等多方面功能恢复。多项研究显示ERAS在肝移植患者中的应用是安全的,并且在控制并发症、缩短住院时间、减少医疗费用等不同维度显示出积极作用。结论在不增加风险的同时,ERAS能有效促进肝移植患者术后功能恢复。

Objective To review the effect and safety of enhanced recovery after surgery(ERAS)in liver transplant recipients.Methods A comprehensive literature search of Pubmed,Embase,CNKI,etc.was performed using keywords“ERAS”or“fast track”and“liver transplantation”(cut-off date June 3,2020).The relevant literatures on researches of ERAS in liver transplant recipients at home and abroad in recent years were summarized.Results ERAS effectively could promote the functional recovery of postoperative food intake and physical activities through systemic perioperative measures different from conventional management among the liver transplant recipients.In addition,loads of studies had revealed that ERAS was safe for liver transplant recipients with positive effects in different dim ensions such as controlling complications,shortening hospital stays,and reducing medical expenses,etc.Conclusion ERAS can effectively promote functional recovery of liver transplant recipients without increasing risk.