低FODMAPs饮食干预改善腹泻型肠易激综合征症状的临床疗效研究

The Clinical Effect of low FODMAPs Diet Intervention on Improving the Symptoms of Diarrheal Irritable Bowel Syndrome

目的研究低FODMAPs饮食干预改善中-重度腹泻型IBS患者症状的临床疗效,为采取新的治疗手段提供依据。方法方便选取2019年5月—2020年4月该院收治的101例中-重度腹泻型IBS患者为研究对象,随机分为A、B组,A组51例,给予“低FODMAPs饮食+经典IBS饮食”指导。B组50例,给予“经典IBS饮食”指导,比较两组患者干预前后症状评分、排便情况。结果干预后,A组IBS-SSS总分为(182.7±46.6)分,明显低于B组(203.5±61.4)分,差异有统计学意义(P<0.05)。且干预前后A组基线KSC评分与B组比较差异无统计学意义(P>0.05)。结论“低FODMAPs饮食+经典IBS饮食指导”较“经典IBS饮食指导建议”能更有效地改善中-重度腹泻型IBS患者腹痛、腹胀等症状,但对排便情况无明显改善。

Objective To study the clinical efficacy of low-FODMAPs diet intervention to improve the symptoms of patients with moderate to severe diarrhea IBS,and to provide a basis for adopting new treatment methods.Methods 101 patients with moderate to severe diarrhea IBS admitted to the hospital from May 2019 to April 2020 were randomly divided into groups A and B,and 51 patients in group A were given"low FODMAPs diet+classic IBS diet"guidance.Fifty patients in group B were given the"classic IBS diet"instruction,and the symptom scores and defecation status of the two groups were compared before and after intervention.Results After intervention,the total score of IBS-SSS in group A(182.7±46.6)points was significantly lower than that of group B(203.5±61.4)points,the difference between the two groups was statistically significant(P<0.05).And there was no statistically significant difference in baseline KSC score between group A and group B before and after intervention(P>0.05).Conclusion"Low FODMAPs diet+classic IBS diet guidance"can more effectively improve the symptoms of abdominal pain and bloating in patients with moderate to severe diarrhea IBS than"classic IBS diet guidance recommendations",but there is no significant improvement in defecation.