抗生素临床合理应用的药学干预效果

Effect of Pharmaceutical Intervention on the Rational Clinical Application of Antibiotics

目的探讨抗生素临床合理应用的药学干预效果。方法选取2017年1月至2020年1月海门市中医院收治的420例患者为研究对象,随机分为对照组与研究组,每组210例,分别给予常规治疗及药学干预。比较两组抗生素使用合格率、医疗总费用、不合理用药情况、抗生素使用时间及住院时间。结果研究组抗生素使用合格率显著高于对照组,差异有统计学意义(P <0.05)。研究组抗生素医疗费用少于对照组,不合理用药发生率低于对照组,抗生素使用时间与住院时间均短于对照组,差异均有统计学意义(P <0.05)。结论在抗生素临床合理用药中采用药学干预,可提高抗生素的使用合格率,促进临床合理用药,保证患者用药的安全性。

Objective To investigate the pharmaceutical intervention effect of rational clinical application of antibiotics.Methods From January 2017 to January 2020,420 patients were randomly divided into control group and study group,which were given routine treatment and pharmaceutical intervention respectively,with 120 cases in each group.The rate of qualified use of antibiotics,the total cost of medical treatment,the situation of irrational use of antibiotics,the time of using antibiotics and the time of hospitalization were compared between the two groups.Results The qualified rate of antibiotics in the study group was significantly higher than that in the control group,the difference was signifi cant(P<0.05).The medical expenses of antibiotics in the study group were lower than those in the control group,and the incidence of irrational drug use was lower than in the control group,the antibiotic use time and hospital stay were shorter than those in the control group,and the differences were statistically signifi cant(P<0.05).Conclusion The rational use of antibiotics and pharmaceutical intervention can improve the qualified rate of antibiotic application,promote the rational use of antibiotics and ensure the safety of patients.